Investigating
the origins of life.

The Origins Center brings together the best
Dutch research on the origin and evolution of life.

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Why Origins Center

Collaboration leads to breakthroughs

The Origins Center wants the Netherlands to remain at the forefront of international research into the origins and evolution of life. We encourage groundbreaking collaboration, support ambitious projects, and strengthen the visibility and impact of top-level science in our country.

We connect people, talents, knowledge and resources. For a better understanding of the origins and evolution of life on Earth and in the universe; all to the support of science and to better inform the public about Dutch scientific achievements.

Working together, we strive for greater connectivity into the origins of life through an interdisciplinary approach. Achieving this requires effort. The Origins Center contributes to this. We support researchers in our country, setting up innovative partnerships. And, of course, in finding funding for their research ambitions.

Podcasts – Over leven in het Heelal

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What we do

Connecting research. Strengthening impact. Accelerating progress.

The Origins Center connects, supports, and activates scientists with a Research
Agenda and related Knowledge Networks. 

The Origins Center shares groundbreaking research results with the Dutch public. With NEMO Kennislink we build a library with fascinating articles. We make the work of our members visible through TV, newspapers, social media, museums and online channels such as the Universiteit van Nederland. We participate with researchers in the Weekend van de Wetenschap and other festivals.

To give the public and fellow researchers a peek behind the scenes, we bundle the stories of researchers on our website.

Research agenda

Our Research Agenda serves to connect the research done in the Netherlands, and to lead to internationally remarkable results.

Our research themes

The emergence of multicellular life

In multicellular life, cells give up all or part of their autonomy by becoming part of a larger organism. How do cells get that far? Do they benefit from that? And how is it possible that the collective form becomes the new entity that replicates and evolves?

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Our research themes

The emergence of eukaryotes

From the enormous variety of primordial cells (prokaryotes) a eukaryotic cell probably originated once. That cell had a separate cell nucleus and also other organelles, such as mitochondria that regulate cell respiration. This one cell is the ancestor of all the life we can see around us: trees, plants, insects, animals and therefore also us humans.

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Our research themes

The emergence of the living cell (prokaryotes)

The first living cells are called prokaryotes. They have no cell nucleus, so the primal DNA simply floats loose in the cell. What steps resulted in such a first living primordial cell and how did this cell function exactly?

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Our research themes

The emergence of contemporary biochemistry

All life forms we now know have essentially the same biochemistry, based on DNA, RNA and a large group of proteins. But why those? There are many other sets of protein molecules imaginable that are not used. Why is that?

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Our research themes

The emergence of complex relationships between mutations (genotype) and their effects on life (phenotype)

The separation between genotype and phenotype marks an important phase in the development of life. It gives evolution more possibilities to make inventions with the help of mutations and environmental factors.

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Our research themes

The interaction between life and its environment

Life is determined by the environment in which it is located, both the local environment and cthe entire planet. However, in turn life has a major influence on local environments and even the entire planet.

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Our research themes

The emergence of life

At a certain time chemistry turned into biology. Perhaps a chemical ball developed into a primal cell with properties of life. Or did the properties of life first develop into a rock pore? How did all the processes that led to life came together?

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Our research themes

The emergence of Darwinian evolution

Evolution according to Darwin is a continuous cycle of replication and associated mutations. Errors during the replication unintentionally give a system less or more effective properties. Some properties remain, others disappear. Through this selection individual systems appear that have new properties and functions.

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Our research themes

The emergence of life-like functions

Self-replication, metabolism and compartmentalization are at the core of the definition of “life”. Living systems can copy themselves, convert energy and matter, and have a way to protect themselves from the environment. Movement is also very important. These lifelike functions may already have appeared in a lifeless environment.

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Our research themes

The emergence of molecules relevant to life

Life developed around certain groups of minerals and molecules, such as hydrocarbons. But which exactly did it begin with and why? Were these substances present in the oceans – the primordial soup? Why they developed?

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Our research themes

The emergence of the right conditions for the origin of life

The first one and a half billion years were crucial for the emergence of life. Weathering, sedimentation, volcanism, and the onset of plate tectonics led to the right conditions for life to emerge.

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Our research themes

The formation and early evolution of Earth-like planets and moons

For the time being, we assume that life as we know it originated on Earth. Before it could arise, therefore, a habitable planet was needed.

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