This workshop series is designed to cross-pollinate between different areas of research addressing origins of life, including early earth geoscience and prebiotic chemistry. This workshop will foster intellectual cooperation and innovation across the community and thereby give rise to novel research avenues. A central goal is to root models for the emergence of prebiotic pathways in realistic planetary conditions, and fully integrate the dynamics and constraints of early Earth environments into origins hypotheses. Beyond our planet, PCE3 aims to identify planetary conditions that can or cannot give rise to life’s chemistry, thus guiding future missions that target the discovery of habitable worlds.